Annual Conference 2023
Population diversity, its biological
consequences and impact on disease risk
The Royal Society
6-9 Carlton House Terrace
London, SW1Y 5AG
18 October, 2023
It has long been known that people not only differ in DNA sequence from each other- (any two people plucked at random differ by the order of 0.1% of their DNA bases), but the frequencies of many of the nucleotide changes differ in different parts of the world. This means that people living within the same geographic areas or societal groups tend to cluster together as a result of their shared ancestry, while those living further apart may form distinguishable clusters. But migration of peoples leads to admixture, and also differing non-genetic factors in different parts of the world may lead to differential selection and thus also differences in gene frequency. So, our genetic history is complex. This conference attempts to address the extent and functional significance of this diversity. Talks will cover population history, single gene disorders and selection, disease susceptibility, pharmacogenetics and the challenges of precision medicine.
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Speakers
Gavin Band – Head of Statistical Genomics and Group Leader, Wellcome Centre for Human Genetics, University of Oxford.
Hannah Elliott – Post-doctoral Research Fellow, University of Bristol
Garrett Hellenthal – Associate Professor and Group Leader, UCL Genetics Institute
Volker Lauschke – Associate Professor and Group Leader, Karolinska Institute
Mie Rizig – Clinical Senior Research Fellow, Institute of Neurology, UCL.
Ambroise Wonkam – Professor of Medical Genetics, Johns Hopkins School of Medicine, Baltimore
The Adelphi Lecture will be given by Stephanie Malia Fullerton, Professor of Bioethics and Humanities, University of Washington School of Medicine.
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